Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434245 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EHTTCYP3A4HPGD | |
| SCHEMBL12379939 | 0.82 | MEN1 (0.35) | ALDH1A1 | |
| SCHEMBL5588799 | 0.72 | MEN1 (0.41) | ALDH1A1HTTCYP3A4 | |
| SCHEMBL6872181 | 0.64 | PDE3B (0.47) | ALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL6872187 | 0.64 | PDE3B (0.47) | ALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL10906204 | 0.63 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP3A4HPGDFFAR4 | |
| SCHEMBL22683599 | 0.63 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HPGDFFAR4 | |
| SCHEMBL27964706 | 0.63 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HPGDFFAR4 | |
| SCHEMBL12326164 | 0.62 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HPGDFFAR4 | |
| SCHEMBL2633660 | 0.62 | ALDH1A1 (0.59) | ALDH1A1KDM4ECYP3A4HPGDFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090630-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-6822062-B2 | FOR USE IN ADDITION POLYMERIZATION OF OLEFINS | EASTMAN CHEMICAL COMPANY | 2004-11-23 | — | — | US | disclosed |
| US-20040029720-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2004-02-12 | — | — | US | disclosed |
| US-6660677-B1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20020058768-A1 | Supported group 8-10 transition metal Olefin polymerization catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-05-16 | — | — | US | disclosed |
| US-6303720-B1 | E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE | EASTMAN CHEMICAL COMPANY | 2001-10-16 | — | — | US | disclosed |
| EP-1082362-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6103658-A | Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEMICAL COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0973762-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999062968-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1998040374-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |