Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588800 | 1.00 | MEN1 (0.41) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL5588328 | 0.98 | MEN1 (0.39) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL5590202 | 0.86 | LMNA (0.34) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL5590624 | 0.85 | LMNA (0.33) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL14276094 | 0.81 | CNR2 (0.39) | LMNAMAPTHTTNPSR1RAB9A | |
| SCHEMBL14276101 | 0.81 | LMNA (0.34) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL12379939 | 0.80 | MEN1 (0.35) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6430012 | 0.80 | HPGD (0.35) | MEN1HSP90AA1KMT2AATMLMNA | |
| SCHEMBL6430218 | 0.74 | GABRA1 (0.39) | KMT2ALMNACYP1A2TSHRCYP3A4 | |
| SCHEMBL5588837 | 0.72 | GABRA1 (0.38) | KMT2ALMNACYP1A2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| US-20050090630-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-6822062-B2 | FOR USE IN ADDITION POLYMERIZATION OF OLEFINS | EASTMAN CHEMICAL COMPANY | 2004-11-23 | — | — | US | disclosed |
| US-20040029720-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2004-02-12 | — | — | US | disclosed |
| US-6660677-B1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-6620896-B1 | Coordination catalyst comprising transition metal complex of chromium or titanium with indenyl or cyclopentadienyl substituent; oligomerization | EASTMAN CHEMICAL COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-20020058768-A1 | Supported group 8-10 transition metal Olefin polymerization catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-05-16 | — | — | US | disclosed |
| US-6303720-B1 | E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE | EASTMAN CHEMICAL COMPANY | 2001-10-16 | — | — | US | disclosed |
| EP-1082362-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000050475-A1 | MIXED OLEFIN POLYMERIZATION CATALYSTS, PROCESSES EMPLOYING SUCH CATALYSTS, AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-08-31 | — | — | WO | disclosed |
| US-6103658-A | Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEMICAL COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0973762-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999062968-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1998040374-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | MEN1 3377/4885HSP90AA1 4349/4885KMT2A 1733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.