SCHEMBL643450

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10069323	0.84	KDM4E (0.49)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL19511230	0.84	CA12 (0.48)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL10069338	0.82	KDM4E (0.47)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL10069046	0.81	KDM4E (0.46)	KDM4EALDH1A1CA12CA2CA7
	SCHEMBL10069368	0.81	ALDH1A1 (0.46)	KDM4EALDH1A1MAPTPOLBSMN1; SMN2
	SCHEMBL18126609	0.80	SMN1; SMN2 (0.41)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL13603039	0.77	KDM4E (0.48)	KDM4EALDH1A1CA12CA1CA2
	SCHEMBL19809520	0.76	TDP1 (0.50)	ALDH1A1MAPTPOLBSMN1; SMN2TP53
	SCHEMBL28775369	0.76	ALDH1A1 (0.46)	KDM4EALDH1A1MAPTPOLBSMN1; SMN2
	SCHEMBL30884588	0.76	ALDH1A1 (0.46)	KDM4EALDH1A1MAPTPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.