Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468123 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10069323 | 0.91 | KDM4E (0.49) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2558486 | 0.90 | NPC1 (0.44) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10069355 | 0.88 | KDM4E (0.44) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2559609 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL643450 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2556818 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6468002 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL12284075 | 0.79 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10069368 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |