Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 5/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686059 | 0.82 | IDO1 (0.52) | CYP3A4SMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL6434684 | 0.77 | CD44 (0.41) | PIK3CACYP3A4TSHRALDH1A1KDM4E | |
| SCHEMBL15125436 | 0.74 | GAA (0.52) | PIK3CACYP3A4TSHRSMN1; SMN2HPGD | |
| SCHEMBL6429571 | 0.74 | — | — | |
| SCHEMBL31158157 | 0.73 | CYP3A4 (0.48) | PIK3CACYP3A4TSHRSMN1; SMN2HPGD | |
| SCHEMBL17195019 | 0.72 | BRD4 (0.46) | PIK3CACYP3A4TSHRSMN1; SMN2HPGD | |
| SCHEMBL17194909 | 0.72 | BRD4 (0.36) | CYP3A4TSHRALDH1A1KDM4EGAA | |
| SCHEMBL30839749 | 0.72 | CYP3A4 (0.72) | PIK3CACYP3A4TSHRSMN1; SMN2HPGD | |
| SCHEMBL2206282 | 0.72 | CYP3A4 (0.72) | PIK3CACYP3A4TSHRSMN1; SMN2HPGD | |
| SCHEMBL1732673 | 0.71 | MKNK1 (0.44) | SMN1; SMN2S1PR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | PIK3CA 936/4885CYP3A4 25/4885TSHR 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.