SCHEMBL64347

SCHEMBL64347

O=C(O)COc1cc(Cl)ccc1Cl

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.74
TSHR P16473 1/20 0.66
MAPT P10636 1/20 0.63
PTGDR2 Q9Y5Y4 9/20 0.59
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
PTGDR Q13258 4/20 0.56
MRGPRX4 Q96LA9 1/20 0.54
PTGER2 P43116 1/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
TP53 P04637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5389347 0.87 TDP1 (0.77) TDP1TSHRMAPTPTGDR2PTGDR
2,4-Dichlorophenoxyacetic Acid SCHEMBL226803 0.85 TDP1 (1.00) TDP1TSHRMAPTPTGDR2PTGDR
2,4-Dichlorophenoxyacetic Acid SCHEMBL31108925 0.85 TDP1 (1.00) TDP1TSHRMAPTPTGDR2PTGDR
2,4-Dichlorophenoxyacetic Acid SCHEMBL11716042 0.85 TDP1 (1.00) TDP1TSHRMAPTPTGDR2PTGDR
SCHEMBL9722688 0.85 TDP1 (0.54) TDP1TSHRMAPTMEN1KMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 0.85 TDP1 (1.00) TDP1TSHRMAPTPTGDR2PTGDR
2,4-Dichlorophenoxyacetic Acid SCHEMBL4586671 0.84 TDP1 (0.96) TDP1TSHRMAPTPTGDR2PTGDR
2,4-Dichlorophenoxyacetic Acid SCHEMBL7618485 0.84 TDP1 (0.96) TDP1TSHRMAPTPTGDR2PTGDR
SCHEMBL5395902 0.84 MCL1 (0.68) TDP1TSHRMAPTKMT2A
2,4-Dichlorophenoxyacetic Acid SCHEMBL17891942 0.84 TDP1 (0.96) TDP1TSHRMAPTPTGDR2PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082500-A Method for preparing single plant cell 北京艾普希隆生物科技有限公司 2025-06-03 CN claimed
US-4345097-A Chlorination of phenols and phenoxyacetic acids with sulfuryl chloride VERTAC CHEMICAL CORPORATION (US) 1982-08-17 US claimed
CN-120082500-A Method for preparing single plant cell 北京艾普希隆生物科技有限公司 2025-06-03 CN disclosed
CN-119546182-A Method for producing haploid/doubled haploid sunflower plants by microspore culture 科沃施种子欧洲股份两合公司 2025-02-28 CN disclosed
CN-110143932-B Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds 南开大学 2022-09-16 CN disclosed
CN-111493078-A Use of piperazinone derivatives, an accelerator and a method for controlling root parasitic weeds 南开大学 2020-08-07 CN disclosed
CN-110143932-A Piperazinone derivs and preparation method thereof, inhibitor and the method for preventing and treating root parasitism weeds 南开大学 2019-08-20 CN disclosed
WO-2019154284-A1 PIPERAZINONE DERIVATIVE, PREPARATION METHOD THEREFOR, USE THEREOF, ACCELERATOR AND METHOD FOR CONTROLLING ROOT PARASITIC WEEDS 南开大学 2019-08-15 WO disclosed
US-20150148311-A1 NON-SYSTEMIC TGR5 AGONISTS ARDELYX INC (US) 2015-05-28 US disclosed
US-20150148311-A1 NON-SYSTEMIC TGR5 AGONISTS ARDELYX INC (US) 2015-05-28 US disclosed
US-20150148311-A1 NON-SYSTEMIC TGR5 AGONISTS ARDELYX INC (US) 2015-05-28 US disclosed
US-20080256666-A1 METHODS OF IDENTIFYING AND CREATING RUBISCO LARGE SUBUNIT VARIANTS WITH IMPROVED RUBISCO ACTIVITY, COMPOSITIONS AND METHODS OF USE THEREOF PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-10-16 US disclosed
WO-2008121602-A1 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2008-10-09 WO disclosed
US-20080189810-A1 Compositions and Methods of Use of Response Regulators PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-08-07 US disclosed
WO-2006081060-A2 COMPOSITIONS AND METHODS OF USE OF RESPONSE REGULATORS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2006-08-03 WO disclosed
US-20060168692-A1 Compositions and methods of use of response regulators PIONEER HI-BRED INTERNATIONAL, INC. (US) 2006-07-27 US disclosed
EP-0122010-B1 TIMED RELEASE DELIVERY MEANS FOR DELIVERY OF ACTIVE AGENT TO SPATIALLY SEPARATED TERRAIN LOCATIONS AND COMPOSITIONS COMPRISED THEREBY METROPOLITAN MOSQUITO CONTROL DISTRICT (US) 1988-11-02 EP disclosed
US-4345097-A Chlorination of phenols and phenoxyacetic acids with sulfuryl chloride VERTAC CHEMICAL CORPORATION (US) 1982-08-17 US disclosed
US-4326882-A Trichlorophenoxy alkanoic acid free of chlorinated dibenzo-p-dioxins PPG INDUSTRIES, INC. (US) 1982-04-27 US disclosed
US-4293707-A Process for preparing trichlorophenoxy alkanoic acid and hydrolyzable derivatives thereof free of chlorinated dibenzo-p-dioxins PPG INDUSTRIES, INC. (US) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148311-A1 NON-SYSTEMIC TGR5 AGONISTS GLP1R, GPR119, TRHR TDP1 1293/4885TSHR 6/4885MAPT 1499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.