Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ARNT | P27540 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434942 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL25645288 | 0.80 | KMT2A (0.52) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6421053 | 0.79 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6421059 | 0.79 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6415002 | 0.76 | BIRC5 (0.46) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6415008 | 0.76 | BIRC5 (0.46) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL3045614 | 0.74 | MEN1 (0.52) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL25645075 | 0.73 | GAA (0.44) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6503291 | 0.73 | MET (0.52) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL6506319 | 0.73 | MET (0.52) | ALDH1A1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |