Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 12/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11633575 | 0.98 | P4HTM (0.61) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6651827 | 0.87 | P4HTM (0.61) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11632031 | 0.86 | P4HTM (0.59) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11631216 | 0.86 | P4HTM (0.59) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL754198 | 0.86 | P4HTM (0.63) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10932629 | 0.86 | P4HTM (0.46) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5037300 | 0.86 | PLA2G10 (0.58) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL11633386 | 0.84 | P4HTM (0.57) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL11005582 | 0.83 | HIF1A (0.47) | P4HTMLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL21395248 | 0.82 | HCAR2 (0.57) | P4HTMLMNAKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066242-B1 | TOCOPHERYL ESTER OF 5-SUBSTITUTED PICOLINIC ACID, PROCESS FOR ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING IT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | claimed |
| US-4443459-A | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | claimed |
| EP-0066242-A1 | Tocopheryl ester of 5-substituted picolinic acid, process for its production, and pharmaceutical composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-12-08 | — | — | EP | claimed |
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | claimed |
| JP-52083668-A | — | — | None | — | — | JP | disclosed |
| JP-2164808-A | — | — | None | — | — | JP | disclosed |
| EP-0869789-B1 | ANTIVIRAL AGENT | NOVACTYL INC (US) | 2005-11-23 | — | — | EP | disclosed |
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| JP-H02164808-A | SKIN DRUG FOR EXTERNAL USE | SHISEIDO CO LTD | 1990-06-25 | — | — | JP | disclosed |
| EP-0066242-B1 | TOCOPHERYL ESTER OF 5-SUBSTITUTED PICOLINIC ACID, PROCESS FOR ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING IT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | disclosed |
| US-4443459-A | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0066242-A1 | Tocopheryl ester of 5-substituted picolinic acid, process for its production, and pharmaceutical composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1982-12-08 | — | — | EP | disclosed |
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| US-4109000-A | HYPOTENSIVES | NIPPON SHINYAKU CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| JP-S5283668-A | 5-BENZYLPICOLINE DERIVATIVES | NIPPON SHINYAKU CO LTD | 1977-07-12 | — | — | JP | disclosed |