Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6434986 | 0.86 | P4HTM (0.62) | P4HTMLMNAPLA2G10PLA2G2AHIF1A | |
| Hydrochloric Acid SCHEMBL11633575 | 0.84 | P4HTM (0.61) | P4HTMLMNAPLA2G10PLA2G2ATBXAS1 | |
| SCHEMBL5037300 | 0.83 | PLA2G10 (0.58) | P4HTMLMNAPLA2G10PLA2G2ATBXAS1 | |
| SCHEMBL11005582 | 0.80 | HIF1A (0.47) | P4HTMLMNAPLA2G10PLA2G2AHIF1A | |
| SCHEMBL11630275 | 0.79 | MAPK1 (0.54) | P4HTMLMNAKDM4EPKML3MBTL1 | |
| SCHEMBL10932632 | 0.79 | CALM1 (0.44) | P4HTMLMNAPLA2G10PLA2G2ATBXAS1 | |
| SCHEMBL11633297 | 0.78 | MMP13 (0.59) | HIF1AALDH1A1CYP1A2KMT2AL3MBTL1 | |
| SCHEMBL11629400 | 0.76 | PARP1 (0.54) | LMNAHIF1AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11630338 | 0.76 | GABRA1 (0.52) | LMNAKDM4EALDH1A1CYP1A2MAPT | |
| Hydrochloric Acid SCHEMBL11631612 | 0.75 | GABRA1 (0.51) | LMNAKDM4EALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066242-B1 | TOCOPHERYL ESTER OF 5-SUBSTITUTED PICOLINIC ACID, PROCESS FOR ITS PRODUCTION, AND PHARMACEUTICAL COMPOSITION CONTAINING IT | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1985-08-07 | — | — | EP | claimed |
| US-4443459-A | α-Tocopheryl ester of 5-substituted picolinic acid and hypotensive composition containing it | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1984-04-17 | — | — | US | claimed |