Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633297 | 0.84 | MMP13 (0.59) | HIF1AALDH1A1 | |
| SCHEMBL5037300 | 0.83 | PLA2G10 (0.58) | HIF1APLA2G10PLA2G2AALDH1A1MAPT | |
| SCHEMBL11629400 | 0.83 | PARP1 (0.54) | HIF1AHDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL6434986 | 0.83 | P4HTM (0.62) | HIF1APLA2G10PLA2G2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11633575 | 0.81 | P4HTM (0.61) | HIF1APLA2G10PLA2G2AALDH1A1MAPT | |
| SCHEMBL10932629 | 0.80 | P4HTM (0.46) | HIF1APLA2G10PLA2G2AALDH1A1MAPT | |
| SCHEMBL11630275 | 0.79 | MAPK1 (0.54) | KDM4EP4HTMLMNA | |
| SCHEMBL11383635 | 0.77 | P4HTM (0.73) | HIF1AHDAC6ALDH1A1MAPTNPC1 | |
| SCHEMBL10932632 | 0.76 | CALM1 (0.44) | PLA2G10PLA2G2AP4HTMLMNA | |
| SCHEMBL5471298 | 0.75 | PLA2G10 (0.66) | HIF1APLA2G10PLA2G2AHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0139917-A1 | Pharmaceutical preparations, acylated hydrazine derivatives, methods for their preparation | CIBA-GEIGY AG (CH) | 1985-05-08 | — | — | EP | disclosed |