Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.57 |
| ▸ | FLT1 | P17948 | 9/20 | 0.57 |
| ▸ | KDR | P35968 | 9/20 | 0.57 |
| ▸ | EGFR | P00533 | 6/20 | 0.57 |
| ▸ | FLT4 | P35916 | 5/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431414 | 0.92 | KDR (0.60) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431154 | 0.87 | FLT1 (0.52) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431608 | 0.85 | FLT1 (0.55) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6433338 | 0.85 | FLT1 (0.67) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431137 | 0.84 | EHMT2 (0.45) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6434261 | 0.84 | FLT1 (0.56) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6437938 | 0.84 | FLT1 (0.53) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6430749 | 0.83 | FGFR1 (0.75) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL6434695 | 0.82 | FGFR1 (0.77) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431459 | 0.80 | RET (0.54) | FGFR1FLT1KDREGFRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929526-B1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ASTRAZENECA AB (SE) | 2005-07-27 | — | — | EP | claimed |