Hypophosphorous Acid

Hypophosphorous Acid

SCHEMBL6435459

O=[PH2]O.Oc1ccc(C(c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 2/20 0.52
GAA P10253 2/20 0.52
KMT2A Q03164 1/20 0.52
IDO1 P14902 1/20 0.47
TDO2 P48775 1/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
ESR1 P03372 2/20 0.43
ESR2 Q92731 2/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
SLC6A2 P23975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL982047 0.89 IDO1 (0.56) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL36791 0.89 IDO1 (0.56) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL22694327 0.89 IDO1 (0.56) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL19314626 0.89 IDO1 (0.56) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL27708306 0.86 IDO1 (0.54) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL3045847 0.82 MMP3 (0.64) TDP1ALDH1A1GAAKMT2AIDO1
SCHEMBL22238270 0.82 MMP3 (0.64) TDP1ALDH1A1GAAKMT2AIDO1
Phenol SCHEMBL1355272 0.81 TDP1 (0.65) TDP1ALDH1A1GAAKMT2AIDO1
Phenol SCHEMBL28872766 0.81 TDP1 (0.65) TDP1ALDH1A1GAAKMT2AIDO1
Dimethylamine SCHEMBL10775338 0.80 TDP1 (0.48) TDP1ALDH1A1GAAKMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268665-B1 FLAME RETARDANT PHOSPHORUS ELEMENT-CONTAINING EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES INC (US) 2005-11-02 EP claimed