Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.75 |
| ▸ | CNR2 | P34972 | 6/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207067 | 0.83 | LAP3 (0.55) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6432979 | 0.82 | CNR1 (0.69) | CNR1CNR2SMN1; SMN2RAB9AHTT | |
| SCHEMBL15709156 | 0.82 | CNR1 (0.59) | CNR1CNR2ALDH1A1MEN1KMT2A | |
| SCHEMBL5869510 | 0.81 | CNR1 (0.58) | CNR1CNR2RAB9A | |
| SCHEMBL5869521 | 0.81 | CNR1 (0.58) | CNR1CNR2RAB9A | |
| SCHEMBL5869529 | 0.81 | CNR1 (0.58) | CNR1CNR2RAB9A | |
| SCHEMBL9493656 | 0.80 | CNR1 (0.61) | CNR1CNR2SMN1; SMN2RAB9AHTT | |
| SCHEMBL6436285 | 0.79 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL28041163 | 0.79 | CNR1 (1.00) | CNR1CNR2SMN1; SMN2HTT | |
| SCHEMBL9832121 | 0.79 | CNR1 (0.69) | CNR1CNR2SMN1; SMN2RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224163-B1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2005-03-30 | — | — | EP | disclosed |
| CN-1184964-C | Use of carbonylamino derivatives against CNS disorders | HOFFMANN LA ROCHE (CH) | 2005-01-19 | — | — | CN | disclosed |
| US-6548522-B1 | N-substituted 2,2-diphenylacetamide or N-substituted 2-phenyl-2-pyridinylacetamide | HOFFMANN-LA ROCHE INC. | 2003-04-15 | — | — | US | disclosed |