Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.65 |
| ▸ | CNR2 | P34972 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334318 | 0.95 | NAAA (0.72) | CNR1NAAACNR2LMNAPAX8 | |
| SCHEMBL6434483 | 0.93 | NAAA (0.75) | CNR1NAAACNR2LMNAPAX8 | |
| SCHEMBL2333785 | 0.93 | NAAA (0.75) | CNR1NAAACNR2LMNAPAX8 | |
| SCHEMBL6432979 | 0.89 | CNR1 (0.69) | CNR1CNR2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7603553 | 0.84 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL4986402 | 0.83 | NAAA (0.61) | CNR1NAAACNR2LMNAPAX8 | |
| SCHEMBL7599242 | 0.83 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL4055326 | 0.83 | CNR1 (0.69) | CNR1CNR2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20803506 | 0.83 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL13963328 | 0.83 | CNR1 (0.69) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531816-B1 | SPIROCYCLIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF | LUNDBECK & CO AS H (DK) | 2009-01-21 | — | — | EP | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| EP-1224163-B1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2005-03-30 | — | — | EP | disclosed |
| CN-1184964-C | Use of carbonylamino derivatives against CNS disorders | HOFFMANN LA ROCHE (CH) | 2005-01-19 | — | — | CN | disclosed |
| US-6548522-B1 | N-substituted 2,2-diphenylacetamide or N-substituted 2-phenyl-2-pyridinylacetamide | HOFFMANN-LA ROCHE INC. | 2003-04-15 | — | — | US | disclosed |
| EP-1224163-A1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027070-A1 | USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-19 | — | — | WO | disclosed |