Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.73 |
| ▸ | CCR2 | P41597 | 1/20 | 0.66 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6439390 | 0.84 | F10 (0.85) | F10F2 | |
| Acetic Acid SCHEMBL6436692 | 0.84 | F10 (0.95) | F10F2 | |
| SCHEMBL3963296 | 0.83 | CCR2 (0.72) | F10CCR2 | |
| Hydrochloric Acid SCHEMBL6434381 | 0.82 | F10 (0.98) | F10F2 | |
| SCHEMBL6432819 | 0.80 | F10 (0.84) | F10CCR2F2 | |
| SCHEMBL6433546 | 0.80 | CCR2 (0.67) | F10CCR2 | |
| SCHEMBL6308101 | 0.79 | CCR2 (1.00) | CCR2 | |
| SCHEMBL699964 | 0.76 | CCR2 (0.65) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL6435718 | 0.76 | F10 (0.75) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6436035 | 0.76 | F10 (0.96) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |