Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.84 |
| ▸ | F2 | P00734 | 1/20 | 0.74 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.74 |
| ▸ | CCR2 | P41597 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963187 | 0.91 | PLA2G10 (0.83) | F10F2PLA2G10CCR2 | |
| SCHEMBL27497454 | 0.88 | PLA2G10 (0.74) | F10F2PLA2G10CCR2 | |
| SCHEMBL12589590 | 0.87 | F10 (1.00) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL7717765 | 0.87 | F10 (0.85) | F10F2PLA2G10 | |
| Iodide SCHEMBL7424045 | 0.86 | CCR2 (0.71) | F10F2PLA2G10CCR2 | |
| SCHEMBL6433216 | 0.86 | F10 (0.78) | F10F2PLA2G10CCR2 | |
| SCHEMBL6434124 | 0.86 | CCR2 (0.66) | F10F2PLA2G10CCR2 | |
| SCHEMBL6435748 | 0.84 | F10 (1.00) | F10F2PLA2G10 | |
| Acetic Acid SCHEMBL6436891 | 0.84 | F10 (0.94) | F10F2 | |
| SCHEMBL6435781 | 0.84 | F10 (0.82) | F10F2PLA2G10CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |