Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863691 | 0.81 | ALDH1A1 (0.42) | KDM4CPTPN1PDE4B | |
| SCHEMBL6362992 | 0.79 | KDM4C (0.42) | KDM4CPTPN1PDE4BSLC6A3DHFR | |
| SCHEMBL24373929 | 0.76 | KDM4C (0.43) | KDM4CPTPN1PDE4BSLC6A3P2RX3 | |
| SCHEMBL30918744 | 0.75 | ALDH1A1 (0.40) | KDM4CPTPN1PDE4BDHFR | |
| SCHEMBL5773668 | 0.74 | PTPN1 (0.40) | PTPN1PDE4BPOLB | |
| SCHEMBL9961901 | 0.74 | KDM4E (0.43) | PTPN1PDE4BSLC6A3 | |
| SCHEMBL10468410 | 0.74 | PTPN1 (0.39) | KDM4CPTPN1PDE4B | |
| SCHEMBL6562646 | 0.74 | PTPN1 (0.37) | KDM4CPTPN1PDE4BGCGRDHFR | |
| SCHEMBL21305297 | 0.74 | PTGDR2 (0.42) | PTPN1PDE4BPOLB | |
| SCHEMBL30705020 | 0.74 | PDE4B (0.39) | PTPN1PDE4BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943191-B1 | Disubstituted lavendustin A analogs and pharmaceutical composition comprising the analogs | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-09-13 | — | — | US | disclosed |
| EP-1367046-A9 | Disubstituted lavendustin A analogs and pharmaceutical compositions comprising the analogs | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-05-12 | — | — | EP | disclosed |
| EP-1367046-A1 | Disubstituted lavendustin A analogs and pharmaceutical compositions comprising the analogs | THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-12-03 | — | — | EP | disclosed |