SCHEMBL6435871

SCHEMBL6435871

C=CC(=O)NC1CCCC2CCCCC21

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.35
FGFR4 P22455 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
NPC1 O15118 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33
MAPK3 P27361 2/20 0.33
TEAD1 P28347 2/20 0.33
EPHX1 P07099 6/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
EPHX2 P34913 1/20 0.32
SMYD3 Q9H7B4 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9147601 0.82 TAS1R3 (0.42) FGFR1FGFR4TAS1R3TAS1R1NPC1
SCHEMBL8362132 0.82 TAS1R3 (0.42) FGFR1FGFR4TAS1R3TAS1R1NPC1
SCHEMBL9151004 0.82 TAS1R3 (0.42) FGFR1FGFR4TAS1R3TAS1R1NPC1
SCHEMBL22784002 0.78 NPC1 (0.52) NPC1SMN1; SMN2HTTGAAEPHX1
SCHEMBL13951142 0.78 HPGD (0.37) TAS1R3TAS1R1NPC1SMN1; SMN2GAA
SCHEMBL12200686 0.76 CPB2 (0.35) TAS1R3TAS1R1NPC1RAB9AALDH1A1
SCHEMBL12198730 0.76 CPB2 (0.35) NPC1RAB9AMAPTKDM4EALDH1A1
SCHEMBL19409138 0.76 TAS1R3 (0.38) FGFR1FGFR4TAS1R3TAS1R1NPC1
SCHEMBL19409147 0.76 FGFR4 (0.34) FGFR1FGFR4TAS1R3TAS1R1NPC1
SCHEMBL7735033 0.76 PSEN1 (0.46) NPC1SMN1; SMN2EPHX1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1013709-B1 Hindered amine compound, resin composition, polyurethane fiber and production method and use thereof TOYO BOSEKI (JP) 2005-03-09 EP disclosed
US-6486238-B1 Hindered amine compound, resin composition, polyurethane fiber and production method and use thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 2002-11-26 US disclosed
EP-1013709-A1 Hindered amine compound, resin composition, polyurethane fiber and production method and use thereof Toyo Boseki Kabushiki Kaisha (JP) 2000-06-28 EP disclosed