SCHEMBL6435909

SCHEMBL6435909

CCC(C(=O)[O-])C1CCCCC1.CCC(C(=O)[O-])C1CCCCC1.[Ni+2]

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.45
EPHX1 P07099 4/20 0.40
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.34
EPHX2 P34913 2/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
MMP2 P08253 2/20 0.33
CA9 Q16790 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6436533 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL6436049 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL6434886 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL2199103 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL6435945 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
Lithium Ion SCHEMBL3888071 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL6434336 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL3421978 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL2199113 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A
SCHEMBL7630887 0.96 SHBG (0.45) SHBGEPHX1CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5260499-A Nickel compound, phosphine compound, organoaluminum compound, perfluorosulfonate polymer PHILLIPS PETROLEUM COMPANY (US) 1993-11-09 US claimed
US-5166114-A Coordination catalyst of organoaluminum compound, phosphine and perfluorosulfonate polymer for polymerization of ethylene PHILLIPS PETROLEUM COMPANY (US) 1992-11-24 US claimed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed
US-5260499-A Nickel compound, phosphine compound, organoaluminum compound, perfluorosulfonate polymer PHILLIPS PETROLEUM COMPANY (US) 1993-11-09 US disclosed
US-5166114-A Coordination catalyst of organoaluminum compound, phosphine and perfluorosulfonate polymer for polymerization of ethylene PHILLIPS PETROLEUM COMPANY (US) 1992-11-24 US disclosed
US-4373074-A CATALYST CONSISTING OF DIALKYLALUMINUM HALIDE, ORGANIC NICKEL COMPOUND, AND ACTIVE HYDROGEN COMPOUND NIPPON PAINT CO., LTD. (JP) 1983-02-08 US disclosed
US-4284704-A Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt EASTMAN KODAK COMPANY (US) 1981-08-18 US disclosed
US-4028429-A ORGANONICKEL-ALUMINUM-AMINEPHOSPHINE COMPLEX E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-07 US disclosed
US-4025570-A REACTION OF ETHYLENE WITH 1,3-DIENE; CATALYST OF NICKEL, HYDROCARBYLALUMINUM HALIDE, AND ARYL PHOSPHINITE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-24 US disclosed