Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2199113 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6436533 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6434886 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6435945 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6434336 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL2199103 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL3421978 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6435909 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL6436049 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A | |
| SCHEMBL7630887 | 0.96 | SHBG (0.45) | SHBGEPHX1CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117954722-A | Method for synchronously realizing repair and surface coating of waste lithium ion battery positive electrode material regeneration | 中南大学 | 2024-04-30 | — | — | CN | claimed |
| US-11646419-B2 | Materials with extremely durable intercalation of lithium and manufacturing methods thereof | Group 14 Technologies, Inc. (US) | 2023-05-09 | — | — | US | claimed |
| US-20230058348-A1 | NOVEL MATERIALS WITH EXTREMELY DURABLE INTERCALATION OF LITHIUM AND MANUFACTURING METHODS THEREOF | GROUP14 TECHNOLOGIES INC (US) | 2023-02-23 | — | — | US | claimed |
| US-4364847-A | TO IMPROVE YIELD OF GASOLINE | UOP INC. (US) | 1982-12-21 | — | — | US | claimed |
| EP-4743400-A1 | GROUP 14 - GROUP 1 CATHODE | Group14 Technologies, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2026063980-A9 | PROCESS FOR MANUFACTURING HARD CARBON WITH PARTICLE MORPHOLOGY CONTROL STRATEGY | GROUP14 TECHNOLOGIES, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| US-12606443-B2 | Manufacturing of silicon-carbon composites materials | GROUP14 TECHNOLOGIES, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-12597597-B2 | Passivated silicon-carbon composite materials | GROUP14 TECHNOLOGIES, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-12577114-B2 | Silicon-carbon composites | GROUP14 TECHNOLOGIES, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4707235-A1 | MANUFACTURING OF SILICON-CARBON COMPOSITES MATERIALS | Group14 Technologies, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-12562381-B2 | Nano-featured porous silicon materials | GROUP14 TECHNOLOGIES, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-12537192-B2 | Composites of porous nano-featured silicon materials and carbon materials | GROUP14 TECHNOLOGIES, INC. (US) | 2026-01-27 | — | — | US | disclosed |
| US-6652608-B1 | Fuel compositions exhibiting improved fuel stability | OCTANE INTERNATIONAL, LTD. | 2003-11-25 | — | — | US | disclosed |
| US-6492064-B1 | EQUIMOLAR MIXTURE OF ETHYLENE CARBONATE, DIMETHYL CARBONATE AND DIETHYL CARBONATE; LITHIUM SALT OF HIGH IONIC MOBILITY, SUCH AS LIPF6; GOOD CYCLE LIFE, STABLILITY AND DISCHARGE CHARACTERISTICS; PORTABLE ELECTRONICS, SPACE VEHICLES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-10 | — | — | US | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
| EP-0565715-A1 | LIQUEFIED GAS FUEL FOR GENERATING HIGHLY LUMINOUS COLORED FLAME | YOSHIBI, CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-4364847-A | TO IMPROVE YIELD OF GASOLINE | UOP INC. (US) | 1982-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12597597-B2 | Passivated silicon-carbon composite materials | CD4, CD2, LBR | SHBG 1025/4885EPHX1 4733/4885CYP2C9 2745/4885 |
| US-12537192-B2 | Composites of porous nano-featured silicon materials and carbon materials | SCN2B, ASIC1, SCNN1B | SHBG 4354/4885EPHX1 4423/4885CYP2C9 3366/4885 |
| US-12606443-B2 | Manufacturing of silicon-carbon composites materials | DSTN, CRY1, CACNG1 | SHBG 1734/4885EPHX1 4788/4885CYP2C9 3153/4885 |
| US-12577114-B2 | Silicon-carbon composites | CD68, CD4, MKI67 | SHBG 1612/4885EPHX1 4498/4885CYP2C9 2654/4885 |
| US-12562381-B2 | Nano-featured porous silicon materials | SAMM50, CD63, TMEM63A | SHBG 4242/4885EPHX1 4859/4885CYP2C9 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.