SCHEMBL643597

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL642237	0.84	ABCB1 (0.46)	KDM4ETDP1GAADYRK1AMMP2
	SCHEMBL11506396	0.83	TDP1 (0.53)	KDM4ETDP1POLBGAAFUT7
	SCHEMBL643484	0.77	RAB9A (0.46)	KDM4ETDP1POLBGAADYRK1A
	SCHEMBL642185	0.76	HPGD (0.50)	KDM4ETDP1POLBGAAFUT7
	SCHEMBL24750118	0.73	KDM4E (0.51)	KDM4ETDP1POLBGAAFUT7
	SCHEMBL30768370	0.73	KDM4E (0.51)	KDM4ETDP1POLBGAAFUT7
	SCHEMBL642684	0.72	KMT2A (0.39)	MAPTKMT2AKCNH2ABCB1
	SCHEMBL642523	0.72	GAA (0.47)	KDM4EPOLBGAAELAVL3ALDH1A1
	SCHEMBL10069376	0.72	CA12 (0.40)	KDM4ETDP1POLBGAAFUT7
	SCHEMBL16742309	0.72	TDP1 (0.70)	KDM4ETDP1POLBGAAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.