SCHEMBL642185

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9818700	0.76	SIGMAR1 (0.43)	HPGDLMNAMEN1MAPTKMT2A
	SCHEMBL643597	0.76	KDM4E (0.49)	HPGDLMNAMMP2MMP14HSP90AB1
	SCHEMBL644093	0.73	DRD1 (0.42)	HPGDMMP2MMP14HSP90AB1DYRK1A
	SCHEMBL643243	0.73	LTB4R (0.38)	MEN1KMT2AABCB1
	SCHEMBL2643783	0.73	ELAVL3 (0.41)	HPGDMMP2MMP14HSP90AB1DYRK1A
	SCHEMBL642737	0.71	PGAM1 (0.43)	HPGDMMP2MMP14HSP90AB1DYRK1A
	SCHEMBL2657238	0.69	DYRK1A (0.39)	HPGDLMNAMMP2MMP14HSP90AB1
	SCHEMBL8464272	0.68	AR (0.45)	KDM4EMAPTALDH1A1CYP3A4GSK3B
	SCHEMBL16250484	0.67	LMNA (1.00)	HPGDLMNAKDM4EMEN1KMT2A
	SCHEMBL29136473	0.65	LMNA (0.74)	HPGDLMNAKDM4EMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.