Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203718 | 0.76 | ALDH1A1 (0.38) | CYP2C19HIF1ACYP2D6ALDH1A1TSHR | |
| SCHEMBL7201967 | 0.76 | ALDH1A1 (0.38) | CYP2C19HIF1ACYP2D6ALDH1A1TSHR | |
| SCHEMBL7203715 | 0.76 | ALDH1A1 (0.38) | CYP2C19HIF1ACYP2D6ALDH1A1TSHR | |
| SCHEMBL25477181 | 0.76 | ALDH1A1 (0.52) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL6372899 | 0.74 | KCNN4 (0.46) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL6372896 | 0.74 | KCNN4 (0.46) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL6372894 | 0.74 | KCNN4 (0.46) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL3363882 | 0.73 | CES1 (0.44) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL17313147 | 0.73 | CYP1A2 (0.46) | KCNN4CES1CYP2C19HIF1ACYP1A2 | |
| SCHEMBL28405954 | 0.73 | KCNN4 (0.44) | KCNN4CES1CYP2C19HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529056-A2 | POST-CLEAVAGE SULFUR DEPROTECTION FOR CONVERGENT PROTEIN SYNTHESIS BY CHEMICAL LIGATION | Geneprot, Inc. (CH) | 2005-05-11 | — | — | EP | disclosed |
| WO-2003106615-A2 | POST-CLEAVAGE SULFUR DEPROTECTION FOR CONVERGENT PROTEIN SYNTHESIS BY CHEMICAL LIGATION | GENEPROT, INC. (CH) | 2003-12-24 | — | — | WO | disclosed |