Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438499 | 0.92 | MAPT (0.60) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6456408 | 0.92 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL6435792 | 0.91 | SMN1; SMN2 (0.56) | ALDH1A1KMT2ARAB9AMAPTL3MBTL1 | |
| SCHEMBL3914094 | 0.88 | MAPT (0.67) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3923527 | 0.81 | KDM4E (0.70) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL3918270 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KMT2AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL3924310 | 0.81 | MAPT (0.78) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL3923763 | 0.80 | MAPT (0.66) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6438921 | 0.77 | KMT2A (0.52) | ALDH1A1KMT2AMEN1RAB9APOLB | |
| SCHEMBL6436355 | 0.76 | KMT2A (0.54) | ALDH1A1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492783-A1 | 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | Axxima Pharmaceuticals AG (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084947-A1 | 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2003-10-16 | — | — | WO | disclosed |