Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.52 |
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923638 | 0.88 | TLR2 (0.62) | KMT2AMEN1MAPTTLR2ALDH1A1 | |
| SCHEMBL6435397 | 0.84 | KMT2A (0.53) | KMT2AMEN1NOD1TP53MAPT | |
| SCHEMBL6438499 | 0.84 | MAPT (0.60) | KMT2AMEN1NOD1TNFTP53 | |
| SCHEMBL6437614 | 0.82 | KMT2A (0.51) | KMT2AMEN1NOD1TNFTP53 | |
| SCHEMBL3914193 | 0.82 | TLR2 (0.67) | KMT2ATP53MAPTCNR2TLR2 | |
| SCHEMBL3923711 | 0.81 | TLR2 (0.60) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL6438921 | 0.81 | KMT2A (0.52) | KMT2AMEN1NOD1TNFNPC1 | |
| SCHEMBL6465710 | 0.79 | KMT2A (0.49) | KMT2AMEN1NOD1MAPTNPC1 | |
| SCHEMBL6438040 | 0.78 | KMT2A (0.51) | KMT2AMEN1NOD1TP53MAPT | |
| SCHEMBL6456408 | 0.78 | ALDH1A1 (0.60) | KMT2AMEN1NOD1TNFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492783-A1 | 4,5,6,7-TRETRAHYDROBENZO(B) THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | Axxima Pharmaceuticals AG (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084947-A1 | 4,5,6,7-TRETRAHYDROBENZO[B] THIOPHENE DERIVATIVES AND METHODS FOR MEDICAL INTERVENTION AGAINST MYCROBACTERIAL INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2003-10-16 | — | — | WO | disclosed |