Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.71 |
| ▸ | CNR2 | P34972 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20803506 | 0.84 | CNR1 (0.69) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL6436285 | 0.84 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL13963328 | 0.84 | CNR1 (0.69) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL4055326 | 0.84 | CNR1 (0.69) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL7599242 | 0.84 | CNR1 (0.69) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL2334318 | 0.83 | NAAA (0.72) | CNR1CNR2 | |
| SCHEMBL17749476 | 0.83 | CNR1 (0.67) | CNR1CNR2HTTSMN1; SMN2 | |
| SCHEMBL6434483 | 0.81 | NAAA (0.75) | CNR1CNR2HTT | |
| SCHEMBL1231957 | 0.81 | CNR1 (0.65) | CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL5099409 | 0.81 | CNR1 (0.65) | CNR1CNR2HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891344-B1 | ALPHA-1 ADRENERGIC RECEPTOR ANTAGONISTS | SOD CONSEILS RECH APPLIC (FR) | 2002-12-18 | — | — | EP | disclosed |
| US-6300499-B1 | α1-adrenergic receptor antagonists | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-10-09 | — | — | US | disclosed |
| EP-0891344-A1 | ALPHA 1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997037983-A1 | α1-ADRENERGIC RECEPTOR ANTAGONISTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1997-10-16 | — | — | WO | disclosed |