Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3679333 | 0.80 | PDK2 (0.34) | PTGER3PTGER2 | |
| SCHEMBL1576228 | 0.69 | DUT (0.34) | — | |
| SCHEMBL23364138 | 0.68 | DUT (0.37) | — | |
| SCHEMBL23364135 | 0.68 | DUT (0.37) | — | |
| SCHEMBL2850230 | 0.68 | DUT (0.33) | — | |
| SCHEMBL24795965 | 0.68 | DUT (0.33) | — | |
| SCHEMBL24795959 | 0.68 | PDK2 (0.41) | PTGER3PTGER2 | |
| SCHEMBL21389332 | 0.68 | DUT (0.33) | — | |
| SCHEMBL28526467 | 0.68 | DUT (0.33) | — | |
| SCHEMBL1401084 | 0.68 | PDK2 (0.41) | PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453503-A4 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK & CO INC (US) | 2005-03-30 | — | — | EP | disclosed |
| EP-1513589-A1 | 1,5-DISUBSTITUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE DISEASES SUCH AS GLAUCOMA | MERCK FROSST CANADA INC. (CA) | 2005-03-16 | — | — | EP | disclosed |
| EP-1453503-A2 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | Merck & Co., Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003103772-A1 | 1,5-DISTRIBUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TEATMENT OF EYE DISEASES SUCH AS GLAUCOMA | MERCK FROSST CANADA & CO. (CA) | 2003-12-18 | — | — | WO | disclosed |
| WO-2003047417-A2 | EP4 RECEPTOR AGONIST, COMPOSITIONS AND METHODS THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | disclosed |