SCHEMBL6436788

SCHEMBL6436788

Cc1ccccc1-c1ccc(CCC[C@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C)c2ccccc2)C(C)(C)C)cc1

nearest known ligand 0.79

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 20/20 0.79
MMP3 P08254 12/20 0.79
MMP9 P14780 3/20 0.70
MMP13 P45452 3/20 0.70
MMP14 P50281 3/20 0.70
BMP1 P13497 2/20 0.70
MMP1 P03956 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114067 1.00 MMP2 (0.79) MMP2MMP3MMP9MMP13MMP14
Hydrochloric Acid SCHEMBL7111451 0.93 MMP2 (0.68) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7109603 0.92 MMP2 (0.66) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7707546 0.92 MMP2 (0.66) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7114064 0.90 MMP2 (0.85) MMP2MMP3MMP9MMP13MMP14
SCHEMBL6436785 0.90 MMP2 (0.85) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7108969 0.90 MMP2 (0.77) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7112511 0.90 MMP2 (0.77) MMP2MMP3MMP9MMP13MMP14
SCHEMBL7108593 0.89 MMP2 (0.64) MMP2MMP3MMP9MMP13MMP14
SCHEMBL6449143 0.87 MMP2 (0.83) MMP2MMP3MMP9MMP13MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050026836-A1 Composition for the treatment of damaged tissue DACK KEVIN NEIL (GB) 2005-02-03 US disclosed
EP-1047665-B1 MATRIX METALLOPROTEASE INHIBITORS PFIZER LTD (GB) 2003-10-22 EP disclosed
US-6350907-B1 PEPTIDE ENZYME INHIBITORS PFIZER INC 2002-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026836-A1 Composition for the treatment of damaged tissue MMP1, SERPINE1, COL14A1 MMP2 19/4885MMP3 28/4885MMP9 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.