Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 9/20 | 0.48 |
| ▸ | F10 | P00742 | 6/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6433147 | 0.85 | CCR2 (0.54) | CCR2CNR1F10F2POLB | |
| Trifluoroacetic Acid SCHEMBL6436827 | 0.85 | CCR2 (0.69) | CCR2CNR1F10F2NTRK1 | |
| SCHEMBL6433082 | 0.83 | CCR2 (0.78) | CCR2F10F2 | |
| Trifluoroacetic Acid SCHEMBL6433228 | 0.81 | F10 (0.72) | CCR2CNR1F10F2 | |
| Trifluoroacetic Acid SCHEMBL6436624 | 0.79 | F10 (0.67) | CCR2CNR1F10F2 | |
| SCHEMBL6433653 | 0.75 | F10 (0.67) | CCR2CNR1F10L3MBTL1 | |
| SCHEMBL6433615 | 0.74 | CCR2 (0.58) | CCR2CNR1F10POLB | |
| SCHEMBL6433153 | 0.73 | POLB (0.44) | CCR2CNR1F10L3MBTL1POLB | |
| SCHEMBL6432426 | 0.72 | CCR2 (0.78) | CCR2CNR1F10NTRK1 | |
| SCHEMBL27718927 | 0.72 | CCR2 (0.58) | CCR2CNR1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |