Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.72 |
| ▸ | F2 | P00734 | 4/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6436624 | 0.96 | F10 (0.67) | F10F2CCR2CNR1 | |
| Trifluoroacetic Acid SCHEMBL6436827 | 0.89 | CCR2 (0.69) | F10F2CCR2CNR1 | |
| Trifluoroacetic Acid SCHEMBL6436682 | 0.84 | F10 (0.84) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6437256 | 0.84 | F10 (1.00) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6433147 | 0.83 | CCR2 (0.54) | F10F2CCR2CNR1 | |
| SCHEMBL6433082 | 0.83 | CCR2 (0.78) | F10F2CCR2 | |
| SCHEMBL6436698 | 0.81 | F10 (0.66) | F10F2CCR2CNR1 | |
| SCHEMBL6436829 | 0.81 | CCR2 (0.55) | F10F2CCR2CNR1 | |
| Trifluoroacetic Acid SCHEMBL6432601 | 0.80 | F10 (0.77) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6439393 | 0.80 | F10 (0.92) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |