SCHEMBL6437203

SCHEMBL6437203

CN(F)S(=O)(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4754969 0.78 CA1 (0.37) CA1CA2CA7CA13
SCHEMBL1008667 0.78 CA1 (0.37) CA1CA2CA7CA13
SCHEMBL488062 0.73 CA1 (0.39) CA1CA2CA7CA13
SCHEMBL30500990 0.73 CA1 (0.39) CA1CA2CA7CA13
SCHEMBL24465429 0.73 CA1 (0.40) CA1CA2CA7CA13
SCHEMBL17878817 0.73 CA1 (0.33) CA1CA2CA7CA13
SCHEMBL4338081 0.71 CA1 (0.37) CA1CA2CA7CA13
SCHEMBL1703393 0.71 CHRM2 (0.32)
SCHEMBL15326227 0.71 CA1 (0.32) CA1CA2CA7CA13
SCHEMBL23033569 0.71 CA1 (0.32) CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1201627-B1 Ring fluorination of non-activated aromatic compounds AIR PROD & CHEM (US) 2005-12-14 EP disclosed
EP-1201628-B1 Electrophilic fluorination AIR PROD & CHEM (US) 2005-12-14 EP disclosed
EP-1201658-B1 N-Fluorotriazinium fluorinating agents AIR PROD & CHEM (US) 2005-08-03 EP disclosed
US-6737525-B2 USEFUL IN FLUORINATING, PREFERABLY IN A NITROMETHANE SOLVENT, CARBANIONIC SPECIES AND/OR ACTIVATED AROMATIC COMPOUNDS AIR PRODUCTS AND CHEMICALS, INC. 2004-05-18 US disclosed
US-6664391-B2 N-fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. 2003-12-16 US disclosed
US-6635760-B2 Fluorinating a substrate selected from unsubstituted aromatic compounds and aromatic compounds having electron withdrawing substituent(s) comprises contacting substrate with a tri(halo or trifluoromethyl) substituted N-fluorotriazinium salt AIR PRODUCTS AND CHEMICALS, INC. 2003-10-21 US disclosed
US-20020123627-A1 N-fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. 2002-09-05 US disclosed
US-20020123657-A1 Electrophilic fluorination AIR PRODUCTS AND CHEMICALS, INC. 2002-09-05 US disclosed
US-20020055662-A1 Ring fluorination of non-activated aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. 2002-05-09 US disclosed
EP-1201658-A1 N-Fluorotriazinium fluorinating agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
EP-1201628-A1 Electrophilic fluorination AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
EP-1201627-A1 Ring fluorination of non-activated aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-05-02 EP disclosed
EP-0572918-B1 Process for selectively ortho-fluorinating substituted aromatic compounds AIR PROD & CHEM (US) 1998-08-05 EP disclosed
EP-0572918-A1 Process for selectively ortho-fluorinating substituted aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-12-08 EP disclosed
US-5233074-A Process for selectively ortho-fluorinating substituted aromatic compounds AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-08-03 US disclosed
US-5227493-A Fluorinated sulfonamide derivatives AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-07-13 US disclosed
US-4828764-A N-Fluoro-N-Perfluoromethyl sulfonamides RESEARCH CORPORATION (US) 1989-05-09 US disclosed
US-4697011-A N-fluoro-N-perfluoromethyl sulfonamides RESEARCH CORPORATION (US) 1987-09-29 US disclosed
EP-0211578-A2 N-fluoro-N-perfluoromethyl sulfonamides Research Corporation (US) 1987-02-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020123657-A1 Electrophilic fluorination PFAS, SRC, SFN CA1 523/4885CA2 178/4885CA7 495/4885
US-20020123627-A1 N-fluorotriazinium fluorinating agents PFAS, AFF1, FFAR3 CA1 605/4885CA2 265/4885CA7 534/4885
US-20020055662-A1 Ring fluorination of non-activated aromatic compounds NAF1, NPM1, AFF1 CA1 910/4885CA2 302/4885CA7 377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.