Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249421 | 0.87 | TYR (0.48) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL6434416 | 0.80 | CHRNB2 (0.39) | TYRCHRNB2CHRNA4TAS1R3TAS1R1 | |
| SCHEMBL6433192 | 0.80 | TYR (0.41) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL6433194 | 0.80 | TYR (0.41) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL6437210 | 0.79 | ESR2 (0.53) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL3164917 | 0.79 | ESR2 (0.53) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL6433955 | 0.79 | TYR (0.45) | TYRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3162433 | 0.79 | ALDH1A1 (0.43) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL29871375 | 0.79 | ALDH1A1 (0.43) | TYRCHRNB2CHRNA4CYP1A2CYP3A4 | |
| SCHEMBL6434521 | 0.78 | ESR2 (0.57) | CYP3A4CYP2D6CYP2C9HDAC2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | claimed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-1134207-A1 | Process for preparing resorcinol derivatives | Pfizer Products Inc. (US) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |