SCHEMBL6437529

SCHEMBL6437529

CSc1ccc(C(O)(c2ccc(CCCOC34OCC(C)(CO3)CO4)cc2)c2ccc(SC)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
EPHX2 P34913 1/20 0.30
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440105 0.80 EPHX2 (0.33) EPHX2NR1H4
SCHEMBL6437534 0.78 ESR1 (0.32)
SCHEMBL13939397 0.74 HRH3 (0.33)
SCHEMBL13940077 0.68 SLC6A4 (0.45) EPHX2NR1H4
SCHEMBL6437151 0.65 SMN1; SMN2 (0.39)
SCHEMBL6437743 0.64 FFAR1 (0.49) EPHX2NR1H4
SCHEMBL31589091 0.63 CA2 (0.53)
SCHEMBL31558448 0.61 DUT (0.39) GAAEPHX2NR1H4
SCHEMBL8641530 0.61 CA2 (0.50)
SCHEMBL16995434 0.61 SLC6A4 (0.41) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506959-A2 Derivatised molecules for mass spectrometry OXFORD GENE TECHNOLOGY IP LIMITED (GB) 2005-02-16 EP disclosed