SCHEMBL643761

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL644524	0.79	POLB (0.49)	POLBGAACYP3A4HPGDCA12
	SCHEMBL4237442	0.76	LMNA (0.54)	POLBGAACA12CA1CA2
	SCHEMBL644182	0.75	CA12 (0.37)	POLBGAAHPGDCA12CA1
	SCHEMBL11505649	0.75	GAA (0.48)	POLBGAACYP3A4HPGDCA12
	SCHEMBL643614	0.73	CNR2 (0.49)	POLBGAACYP3A4HPGDCA12
	SCHEMBL5838605	0.73	KDM4E (0.47)	POLBGAACYP3A4HPGDCA12
	SCHEMBL29971407	0.73	POLB (0.71)	POLBGAACYP3A4HPGDCA12
	SCHEMBL20812825	0.73	POLB (0.71)	POLBGAACYP3A4HPGDCA12
	SCHEMBL8867887	0.73	GAA (0.62)	POLBGAACYP3A4HPGDCA12
	SCHEMBL24104384	0.71	GAA (0.56)	POLBGAACYP3A4HPGDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.