SCHEMBL644524

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19511526	0.87	HPGD (0.52)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL11506306	0.87	PTPN1 (0.41)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL11505649	0.84	GAA (0.48)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL643051	0.84	LMNA (0.50)	POLBGAAHPGDKDM4ECA12
	SCHEMBL642229	0.79	KDM4E (0.43)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL643761	0.79	POLB (0.49)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL7828001	0.76	CYP3A4 (0.50)	POLBCYP3A4PTPN1TSHRALDH1A1
	SCHEMBL643290	0.76	LMNA (0.56)	POLBGAACYP3A4HPGDKDM4E
	SCHEMBL2430731	0.76	LMNA (0.54)	POLBGAACYP3A4KDM4ECA12
	SCHEMBL2770358	0.75	KDM4E (0.55)	GAACYP3A4KDM4ECYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.