Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011725 | 0.83 | IDH1 (0.43) | MAPTNPSR1POLBTP53ALDH1A1 | |
| SCHEMBL147149 | 0.81 | — | — | |
| SCHEMBL17790231 | 0.80 | — | — | |
| SCHEMBL25367591 | 0.80 | LTA4H (0.42) | HPGDKDM4EALDH1A1GAAHTT | |
| SCHEMBL13715998 | 0.79 | — | — | |
| SCHEMBL1170262 | 0.79 | — | — | |
| SCHEMBL5004859 | 0.79 | — | — | |
| SCHEMBL25128131 | 0.79 | MAOB (0.43) | MAPTNPSR1TP53 | |
| SCHEMBL21205126 | 0.79 | MEN1 (0.47) | MAPTDAOPOLBTP53HPGD | |
| SCHEMBL13983569 | 0.75 | ALDH1A1 (0.39) | MAPTDAOPOLBTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1854804-A1 | Heterocyclic metallocene compounds and use thereof in catalyst systems for producing olefin polymers | Basell Polyolefine GmbH (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1157046-B1 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-6822106-B2 | ADDITION POLYMERIZATION USING SILICON BRIDGED METALLOCENES HAVING TRICYCLIC CYCLOPENTADI(THIO)FURAN DERIVATIVE LIGANDS AS CATALYSTS | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-11-23 | — | — | US | disclosed |
| US-6787619-B2 | UTILIZING SILICON BRIDGED METALLOCENES; HIGH MOLECULAR WEIGHT AND YIELD | BASELL POLYOLEFINE GMBH (DE) | 2004-09-07 | — | — | US | disclosed |
| US-20040097669-A1 | Preparation of ethylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2004-05-20 | — | — | US | disclosed |
| US-20030036610-A1 | Process for the preparation of ethylene polymers | EQUISTAR CHEMICALS, LP | 2003-02-20 | — | — | US | disclosed |
| EP-1157046-A1 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001048040-A1 | PROCESS FOR THE PREPARATION OF ETHYLENE POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |