Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435699 | 0.86 | KDM4E (0.56) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL19885733 | 0.86 | KDM4E (0.58) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL18114411 | 0.85 | KDM4E (0.62) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL13596586 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL13174375 | 0.77 | KMT2A (0.53) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL6414370 | 0.77 | PIM1 (0.47) | ALDH1A1HPGDHSD17B10KMT2AXDH | |
| Hydrochloric Acid SCHEMBL4410239 | 0.77 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL6418981 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL6418974 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EALDH1A1HPGD | |
| SCHEMBL19885961 | 0.76 | KDM4E (0.60) | ITGB3ITGA2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |