Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435699 | 0.89 | KDM4E (0.56) | ITGB3ITGA2BPDGFRBPDGFRAHRH3 | |
| SCHEMBL6418981 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BPDGFRBPDGFRAHRH3 | |
| SCHEMBL18114411 | 0.80 | KDM4E (0.62) | ITGB3ITGA2BPDGFRBPDGFRAFGFR1 | |
| SCHEMBL31722181 | 0.78 | KDM4E (0.47) | ITGB3ITGA2BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL19885733 | 0.77 | KDM4E (0.58) | ITGB3ITGA2BPDGFRBPDGFRAKDM4E | |
| SCHEMBL6437692 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BPDGFRBPDGFRAHRH3 | |
| SCHEMBL18114449 | 0.75 | KDM4E (0.67) | ITGB3ITGA2BPDGFRBPDGFRAHRH3 | |
| SCHEMBL6415966 | 0.75 | S1PR1 (0.44) | XDH | |
| SCHEMBL4248638 | 0.74 | SLC6A2 (0.46) | XDHCYP2D6 | |
| SCHEMBL6870508 | 0.74 | PDGFRB (0.65) | PDGFRBPDGFRAFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |