SCHEMBL6437836

SCHEMBL6437836

NCCNS(=O)(=O)C(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CYP3A4 P08684 3/20 0.41
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
FPR2 P25090 1/20 0.33
CYP2C19 P33261 1/20 0.33
MTOR P42345 1/20 0.33
CSNK1A1 P48729 1/20 0.33
MYLK Q15746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
APEX1 P27695 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6433489 0.86 CA2 (0.39) CA1CA2CYP3A4CYP1A2CYP2D6
SCHEMBL28687682 0.76
SCHEMBL6435794 0.75 EPHX1 (0.52) CA1CA2CYP3A4KDM4ECYP1A2
Hydrochloric Acid SCHEMBL927607 0.73 EPHX1 (0.50) CA1CA2CYP3A4KDM4ETP53
SCHEMBL6020798 0.70 CA1 (0.37) CA1CA2
SCHEMBL28271212 0.67 CA2 (0.53) CA1CA2
SCHEMBL3182187 0.67
SCHEMBL28564880 0.67
SCHEMBL28996689 0.67
SCHEMBL6139545 0.66 CA2 (0.54) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982286-B1 Diene compounds and process for preparing the same TAKASAGO PERFUMERY CO LTD (JP) 2005-02-23 EP disclosed
US-6323174-B1 PERFUME COMPOSITION AT LEAST COMPRISING 4-METHYL-5-HEXEN-1-AL TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-27 US disclosed
US-6239324-B1 REACTING A 1,3-BUTADIENE WITH OLEFIN IN PRESENCE OF HYDROPHILIC SOLVENT AND RUTHENIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-05-29 US disclosed
EP-0982286-A2 Diene compounds and process for preparing the same Takasago International Corporation (JP) 2000-03-01 EP disclosed