SCHEMBL6433489

SCHEMBL6433489

NCCCNS(=O)(=O)C(Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
RELA Q04206 4/20 0.36
EPHX1 P07099 1/20 0.35
CYP1A2 P05177 5/20 0.35
THPO P40225 4/20 0.35
CYP2C19 P33261 4/20 0.35
ALOX15 P16050 3/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CASP2 P42575 2/20 0.35
CA12 O43570 2/20 0.35
F13A1 P00488 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA7 P43166 2/20 0.35
CA9 Q16790 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA5B Q9Y2D0 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437836 0.86 CA1 (0.42) CA2CA1CYP1A2THPOCYP2C19
SCHEMBL864359 0.77 EPHX1 (0.59) CA2CA1RELAEPHX1CYP1A2
SCHEMBL7870212 0.71 EPHX1 (0.62) CA2CA1RELAEPHX1CYP1A2
SCHEMBL27007022 0.70 RELA (0.44) CA2CA1RELACYP1A2THPO
SCHEMBL23862451 0.70 EPHX1 (0.46) RELAEPHX1CYP1A2THPOCYP2C19
SCHEMBL28379256 0.70 EPHX1 (0.66) CA2CA1RELAEPHX1CYP1A2
SCHEMBL28375139 0.70 EPHX1 (0.66) CA2CA1RELAEPHX1CYP1A2
SCHEMBL6260144 0.69 CA2 (0.51) CA2CA1EPHX1
SCHEMBL11021489 0.69 CA2 (0.51) CA2CA1EPHX1
SCHEMBL2725750 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0982286-B1 Diene compounds and process for preparing the same TAKASAGO PERFUMERY CO LTD (JP) 2005-02-23 EP disclosed
US-6323174-B1 PERFUME COMPOSITION AT LEAST COMPRISING 4-METHYL-5-HEXEN-1-AL TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-11-27 US disclosed
US-6239324-B1 REACTING A 1,3-BUTADIENE WITH OLEFIN IN PRESENCE OF HYDROPHILIC SOLVENT AND RUTHENIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-05-29 US disclosed
EP-0982286-A2 Diene compounds and process for preparing the same Takasago International Corporation (JP) 2000-03-01 EP disclosed