Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519052 | 0.91 | KDM4E (0.51) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL1646635 | 0.90 | KDM4E (0.57) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL30776193 | 0.86 | MAPT (0.51) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL23207522 | 0.80 | KDM4E (0.62) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL30582921 | 0.78 | KDM4E (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL16238574 | 0.78 | KDM4E (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL886818 | 0.77 | KDM4E (0.57) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL17035908 | 0.75 | ADRB1 (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL231823 | 0.75 | ADRB1 (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 | |
| SCHEMBL30101389 | 0.75 | ADRB1 (0.60) | KDM4ELMNAABL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572237-A1 | COMBINATIONS OF VANILLOID ANTAGONIST AND NSAID FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2005-09-14 | — | — | EP | claimed |
| WO-2004056394-A1 | COMBINATIONS OF A VANILLOID ANTAGONIST AND AN NSAID FOR THE TREATMENT OF PAIN | GLAXO GROUP LIMITED (GB) | 2004-07-08 | — | — | WO | claimed |