Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413535 | 1.00 | DDX3X (0.53) | DDX3XTP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6437966 | 0.88 | ALDH1A1 (0.46) | DDX3XTP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6414744 | 0.88 | ALDH1A1 (0.46) | DDX3XTP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6418807 | 0.85 | MAPT (0.55) | DDX3XTP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6418810 | 0.85 | MAPT (0.55) | DDX3XTP53ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6439515 | 0.82 | MAPT (0.51) | TP53ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6436226 | 0.82 | MAPT (0.51) | TP53ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6421066 | 0.81 | KMT2A (0.54) | DDX3XTP53ALDH1A1HSP90AA1MAPT | |
| SCHEMBL6501740 | 0.79 | SMN1; SMN2 (0.50) | TP53ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6501729 | 0.79 | SMN1; SMN2 (0.50) | TP53ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044270-A1 | OXADIAZOLOPYRAZINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS | 4SC AG (DE) | 2005-05-19 | — | — | WO | disclosed |