Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559156 | 0.79 | SLC6A2 (0.39) | — | |
| SCHEMBL11785888 | 0.74 | SLC6A2 (0.52) | — | |
| SCHEMBL5962327 | 0.73 | ESR1 (0.43) | ALOX5CETP | |
| SCHEMBL11786125 | 0.73 | CYP2A6 (0.36) | — | |
| SCHEMBL30480110 | 0.73 | ATM (0.37) | — | |
| SCHEMBL9718076 | 0.71 | IDO1 (0.39) | — | |
| SCHEMBL19041517 | 0.70 | ESR1 (0.36) | — | |
| SCHEMBL5166148 | 0.70 | CYP3A4 (0.55) | — | |
| SCHEMBL4842726 | 0.69 | PYCR1 (0.39) | — | |
| SCHEMBL6436472 | 0.68 | ALOX5 (0.42) | ALOX5CETPTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250528-C | Cyclic nitrones and pharmaceutical compositions containing them | AWENTIS PHARMACEUTICAL INC (US) | 2006-04-12 | — | — | CN | disclosed |
| EP-1288203-B1 | Cyclic nitrones and pharmaceutical compositions containing them | AVENTIS PHARMA INC (US) | 2005-04-20 | — | — | EP | disclosed |
| CN-1500779-A | Cyclic nitrones and pharmaceutical compositions containing them | ���µ�˹ҩ�﹫˾ | 2004-06-02 | — | — | CN | disclosed |
| CN-1500787-A | Cyclic nitrones and pharmaceutical compositions containing them | ���µ�˹ҩ�﹫˾ | 2004-06-02 | — | — | CN | disclosed |
| EP-1288203-A1 | Cyclic nitrones and pharmaceutical compositions containing them | Aventis Pharmaceuticals Inc. (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5962469-A | PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS | HOECHST MARION ROUSSEL INC. (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1196050-A | Cyclic nitrones and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (US) | 1998-10-14 | — | — | CN | disclosed |
| EP-0863878-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010218-A1 | CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-20 | — | — | WO | disclosed |