Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 11/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440345 | 0.78 | SMN1; SMN2 (0.67) | GSTO1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL6992440 | 0.76 | TP53 (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL8246439 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL6374705 | 0.74 | RAB9A (0.69) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL12346979 | 0.72 | TP53 (0.44) | SMN1; SMN2ALDH1A1CYP1A2TP53L3MBTL1 | |
| SCHEMBL12039939 | 0.72 | NPC1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 | |
| SCHEMBL14582747 | 0.70 | TP53 (0.43) | SMN1; SMN2ALDH1A1CYP1A2TP53L3MBTL1 | |
| SCHEMBL8626453 | 0.68 | POLB (0.60) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL970072 | 0.67 | CA1 (0.60) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| SCHEMBL2664519 | 0.67 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7175977-B2 | Stabilizers for use in thermographic recording materials | AGFA-GEVAERT (BE) | 2007-02-13 | — | — | US | disclosed |
| US-7175977-B2 | Stabilizers for use in thermographic recording materials | AGFA-GEVAERT (BE) | 2007-02-13 | — | — | US | disclosed |
| WO-2005072731-A1 | 3-PHENYL-N- ((1, 3, 4) THIADIAZOL-2-YL) -ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF ESTROGEN-RELATED RECEPTORS FOR THE TREATMENT OF E.G. CANCER, RHEUMATOID ARTHRITIS OR NEUROLOGICAL DISORDERS | X-CEPTOR THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | WO | disclosed |