Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18051653 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL10938162 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL6666006 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL6665999 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL18051642 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL180609 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL230726 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL1374292 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL3146174 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TP53HIF1ACYP3A4MAPK1 | |
| SCHEMBL335609 | 0.81 | THRB (0.49) | ALDH1A1TP53HIF1ACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421141-B1 | POLYESTER COMPOSITIONS OF LOW RESIDUAL ALDEHYDE CONTENT | CIBA SC HOLDING AG (CH) | 2005-03-09 | — | — | EP | claimed |
| US-6255362-B1 | HYDRATED, CROSSLINKED COPOLYACRYLATE CONTAINING SILOXANE, URETHANE AND ETHER GROUPS; CLEAR, DURABLE, FLEXIBLE SOFT CONTACT LENSES | MENICON CO., LTD. (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0937998-A2 | Ocular lens material and process for producing the same | Menicon Co., Ltd. (JP) | 1999-08-25 | — | — | EP | disclosed |