Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22973241 | 0.77 | LMNA (0.33) | — | |
| Acrylic Acid SCHEMBL28233570 | 0.72 | LMNA (0.56) | THRB | |
| Perflexane SCHEMBL30667525 | 0.72 | LMNA (0.56) | THRB | |
| Acrylic Acid SCHEMBL28987257 | 0.72 | LMNA (0.56) | THRB | |
| SCHEMBL12200571 | 0.69 | THRB (0.32) | THRB | |
| Perflubutane SCHEMBL5248912 | 0.69 | LMNA (0.59) | THRB | |
| SCHEMBL12200587 | 0.68 | THRB (0.39) | THRB | |
| SCHEMBL13146827 | 0.67 | — | — | |
| SCHEMBL29809675 | 0.67 | THRB (0.37) | THRB | |
| Acrylic Acid SCHEMBL22151522 | 0.65 | LMNA (0.46) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159317-B1 | NEW BIOMATERIALS | COMMW SCIENT IND RES ORG (AU) | 2005-02-09 | — | — | EP | disclosed |
| US-6503958-B2 | Porous polymers incorporating dihydroperfluoroalkyl acrylates and methacrylates | NOVARTIS AG (CH) | 2003-01-07 | — | — | US | disclosed |
| US-20020103538-A1 | Biomaterials | HUGHES TIMOTHY CHARLES (AU) | 2002-08-01 | — | — | US | disclosed |
| EP-1159317-A1 | NEW BIOMATERIALS | Novartis AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000049058-A1 | NEW BIOMATERIALS | NOVARTIS AG (CH) | 2000-08-24 | — | — | WO | disclosed |