Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440512 | 0.95 | PTGDR2 (0.48) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6442471 | 0.91 | PSEN1 (0.43) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6436468 | 0.86 | PTGDR (0.45) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6439371 | 0.86 | PTGDR2 (0.43) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6442219 | 0.86 | PTGDR2 (0.43) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL3563804 | 0.84 | HTR6 (0.48) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6440415 | 0.83 | PSEN1 (0.48) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6440894 | 0.82 | PTGDR2 (0.47) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6441972 | 0.82 | HTR6 (0.43) | LMNAHTR6PSEN1PSEN2APH1B | |
| SCHEMBL6439680 | 0.81 | HTR6 (0.41) | LMNAHTR6PTGDR2PTGDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |