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Sugi Predict / Compounds / SCHEMBL6439680

SCHEMBL6439680

SCHEMBL6439680

[CH2]COc1c(C)n(S(=O)(=O)c2ccc(Br)cc2)c2ccc(Br)cc12

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 9/20 0.41
▸ PTGDR2 Q9Y5Y4 6/20 0.40
▸ PTGDR Q13258 3/20 0.40
▸ GAA P10253 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6439371 0.95 PTGDR2 (0.43) HTR6PTGDR2PTGDRLMNAMAPT
SCHEMBL6444246 0.93 PTGDR2 (0.48) HTR6PTGDR2PTGDRLMNA
SCHEMBL6436468 0.93 PTGDR (0.45) HTR6PTGDR2PTGDRLMNAMAPT
SCHEMBL6526507 0.88 LMNA (0.47) HTR6GAALMNAMAPT
SCHEMBL6439590 0.84 HTR6 (0.43) HTR6LMNA
SCHEMBL3562247 0.84 HTR6 (0.47) HTR6PTGDR2PTGDRGAALMNA
SCHEMBL6441972 0.84 HTR6 (0.43) HTR6PTGDR2PTGDRGAALMNA
SCHEMBL6440512 0.83 PTGDR2 (0.48) HTR6PTGDR2PTGDRLMNAMAPT
SCHEMBL6440106 0.81 LMNA (0.51) HTR6PTGDR2PTGDRLMNAMAPT
SCHEMBL3556124 0.80 HTR6 (0.45) HTR6PTGDR2PTGDRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567492-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES Suven Life Sciences Limited (IN) 2005-08-31 — — EP claimed
WO-2004048328-A2 N-ARYLSULFONYL-3-AMINOALKOXYINDOLES SUVEN LIFE SCIENCES LIMITED (IN) 2004-06-10 — — WO claimed