Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868648 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL17526390 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL3101113 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL234696 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL20679026 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL17526754 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL17526497 | 0.97 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL979055 | 0.97 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL17526642 | 0.97 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL7209399 | 0.93 | LMNA (0.62) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440407-A | Bispidine compounds and their use in treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-09-03 | — | — | CN | claimed |
| WO-2026101900-A1 | NOVEL HYDROXY CYCLOALKYL CONTAINING LIPID COMPOUNDS AND METHODS OF THEIR USE | Acuitas Therapeutics, Inc. (CA) | 2026-05-15 | — | — | WO | disclosed |
| EP-3558903-B1 | PROCESS FOR PHOSPHORYLATING A COMPLEX ALCOHOL | AVECHO BIOTECHNOLOGY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| US-11753435-B2 | Process | AVECHO BIOTECHNOLOGY LIMITED (AU) | 2023-09-12 | — | — | US | disclosed |
| US-20220106353-A1 | PROCESS | AVECHO BIOTECHNOLOGY LIMITED (AU) | 2022-04-07 | — | — | US | disclosed |
| CN-110662733-A | Method of producing a composite material | 埃维科生物技术有限公司 | 2020-01-07 | — | — | CN | disclosed |
| US-20190330260-A1 | PROCESS | AVECHO BIOTECHNOLOGY LIMITED (AU) | 2019-10-31 | — | — | US | disclosed |
| EP-3558903-A1 | PROCESS | Avecho Biotechnology Limited (AU) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018112512-A1 | PROCESS | PHOSPHAGENICS LIMITED (AU) | 2018-06-28 | — | — | WO | disclosed |
| US-6888030-B2 | Advances in amination | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2005-05-03 | — | — | US | disclosed |
| CN-1144805-C | Bispidine compounds useful in treatment of cardiac arrhythmias | — | 2004-04-07 | — | — | CN | disclosed |
| CN-1440407-A | Bispidine compounds and their use in treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2003-09-03 | — | — | CN | disclosed |
| US-20030078344-A1 | Advances in amination | HUNTSMAN PETROCHEMICAL CORPORATION | 2003-04-24 | — | — | US | disclosed |
| CN-1370167-A | Novel bridged bispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | CN | disclosed |
| EP-1192157-A1 | BISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | AstraZeneca AB (SE) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000077000-A1 | NEW BISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2000-12-21 | — | — | WO | disclosed |
| US-3952068-A | Vinylidene alcohol compositions | JEFFERSON CHEMICAL COMPANY, INC. (US) | 1976-04-20 | — | — | US | disclosed |