SCHEMBL64405

SCHEMBL64405

Cc1cc2ccccc2n1-c1cccc(-n2c(C)cc3ccccc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TSHR P16473 1/20 0.44
PLA2G10 O15496 6/20 0.43
KDM4E B2RXH2 6/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
ALOX15 P16050 2/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
USP2 O75604 1/20 0.41
MYC P01106 1/20 0.41
POLB P06746 1/20 0.41
HSPA1A P0DMV8 1/20 0.41
GAA P10253 1/20 0.41
NR4A1 P22736 1/20 0.41
PTPN7 P35236 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13483671 0.92 TSHR (0.43) ALDH1A1TSHRKDM4EMAPTKMT2A
SCHEMBL1885602 0.90 ALDH1A1 (0.55) ALDH1A1TSHRPLA2G10KDM4EMAPT
SCHEMBL30446730 0.90 ALDH1A1 (0.55) ALDH1A1TSHRPLA2G10KDM4EMAPT
SCHEMBL13425012 0.88 ALDH1A1 (0.47) ALDH1A1TSHRKDM4EMAPTKMT2A
SCHEMBL13948302 0.87 HDAC10 (0.37) ALDH1A1TSHRPLA2G10KDM4EMAPT
SCHEMBL2828527 0.84 PLA2G10 (0.47) ALDH1A1TSHRPLA2G10KDM4EMAPT
SCHEMBL2826918 0.84 FGFR1 (0.47) ALDH1A1TSHRPLA2G10KDM4EMAPT
SCHEMBL5604596 0.82 MAPT (0.40) ALDH1A1TSHRKDM4EMAPTKMT2A
SCHEMBL12345965 0.82 ALDH1A1 (0.43) ALDH1A1TSHRKDM4EMAPTKMT2A
SCHEMBL13241999 0.79 APP (0.46) ALDH1A1TSHRKDM4EMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094810-B1 ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE UDC IRELAND LTD (IE) 2017-08-09 EP disclosed
US-9209417-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-12-08 US disclosed
US-9012034-B2 Organic electroluminescence element UDC IRELAND LIMITED (IE) 2015-04-21 US disclosed
US-8337999-B2 Organic electroluminescent device including at least one layer containing an indole derivative UDC IRELAND LIMITED (IE) 2012-12-25 US disclosed
US-8337999-B2 Organic electroluminescent device including at least one layer containing an indole derivative UDC IRELAND LIMITED (IE) 2012-12-25 US disclosed
US-8129897-B2 Organic electroluminescence element FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8106581-B2 Organic electroluminescence element having concentration variation of hole transporting light-emitting material FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
US-20100193776-A1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2010-08-05 US disclosed
US-20100187985-A1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LIMITED (IE) 2010-07-29 US disclosed
US-20100123126-A1 ORGANIC ELECTROLUMINESCENT ELEMENT FUJIFILM CORPORATION (JP) 2010-05-20 US disclosed
US-20100066243-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE FUJIFILM CORPORATION (JP) 2010-03-18 US disclosed
US-7663309-B2 Organic electroluminescent element having plurality of light emitting layers with specific thicknesses FUJIFILM CORPORATION (JP) 2010-02-16 US disclosed
US-20100026174-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed
US-20100026174-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-02-04 US disclosed
US-20090026938-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2009-01-29 US disclosed
US-20090026939-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LIMITED (IE) 2009-01-29 US disclosed
US-20080180023-A1 Organic electroluminescence element FUJIFILM CORPORATION 2008-07-31 US disclosed
US-20080174236-A1 Organic electroluminescence element FUJIFILM CORPORATION 2008-07-24 US disclosed
WO-2008066195-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE FUJIFILM CORPORATION (JP) 2008-06-05 WO disclosed
US-20080093988-A1 Organic electroluminescent element FUJIFILM CORPORATION 2008-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100066243-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND INDOLE DERIVATIVE IDO1, IDO2, L1CAM ALDH1A1 101/4885TSHR 1593/4885PLA2G10 2082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.